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276© 2019 Indian Journal of Pharmacology Published by Wolters Kluwer - MedknowLurasidone‑induced anemia: Is there a need for hematological monitoring?

By: Kirpekar, Vivek C.
Contributor(s): Faye, Abhijeet D.
Publisher: Mumbai Wolter Kluwer 2019Edition: Vol.51(4), July-Aug.Description: 266-278p.Subject(s): PHARMACOLOGYOnline resources: Click here In: Indian Journal of PharmacologySummary: Lurasidone is a newer drug used for treating schizophrenia and depression in bipolar disorder. Although comparatively safe, some side effects can occur with its use such as akathisia, extrapyramidal reaction, metabolic syndrome, and hyperprolactinemia. Blood dyscrasia with lurasidone is rarely reported in the literature except for few case reports. We present two cases of schizophrenia, treated with lurasidone developing anemia after variable period of treatment and reverting after stopping lurasidone. These cases emphasize the timely monitoring of blood parameters for prevention or early detection of anemia in patients treated with lurasidone.
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Lurasidone is a newer drug used for treating schizophrenia and depression in bipolar disorder. Although comparatively safe, some side effects can occur with its use such as akathisia, extrapyramidal reaction, metabolic syndrome, and hyperprolactinemia. Blood dyscrasia with lurasidone is rarely reported in the literature except for few case reports. We present two cases of schizophrenia, treated with lurasidone developing anemia after variable period of treatment and reverting after stopping lurasidone. These cases emphasize the timely monitoring of blood parameters for prevention or early detection of anemia in patients treated with lurasidone.

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